Editorial

How effective are antidepressants? - p5

Letter: PPI use and oesophageal cancer - p6

Research reviews

Smoking duration the best indicator of COPD progression - p7

Patients with heart failure not being diagnosed in primary care - p8

C-peptide testing can identify risk of hypoglycaemia in insulin-treated type 2 diabetes - p8-9

Composition of vaginal microbiota may increase risk of chlamydia infection - p9

Symposium

Improving the recognition of autism in children and adults - p11-16

Managing patients with severe mental illness and substance misuse - p17-21

SPECIAL REPORTS

Diagnosis and management of migraine in primary care - p23-26

CPD exercise - May 2017 - p27-28

150 YEARS AGO

150 years ago: Blood-letting in eye disorders - p29

100 YEARS AGO

100 years ago: A case of mirror writing - p30

Haslam

How often do patients cry in your consulting room? - p31