Rees J. Is combination therapy effective for overactive bladder? Practitioner 2014; 258 (1772): 9-14

Is combination therapy effective for overactive bladder?

23 Jun 2014Pais-up subscribers

Combining an antimuscarinic with a beta-3 adrenoceptor agonist could improve the symptoms of overactive bladder (OAB), while allowing a lower dose of antimuscarinic and thus reducing side effects, results of an early study suggest. A total of 1,306 patients, at 141 centres across 20 European countries, were randomised in this study. Two-thirds of the patients were women, and all had had symptoms of OAB for 3 months or longer.  [With external links to the current evidence base]

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