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Practitioner 2010 – 254 (1735): 14

Statins may delay the onsets of LUTS

20 Dec 2010Registered users

Statin usage may defer the development of lower urinary tract symptoms (LUTS) and benign prostatic enlargement (BPE) by up to seven years. The Olmsted County study, a huge cohort study that has been running in Minnesota for many years, has produced several important urological papers. The Olmsted County database was used to carry out a retrospective study of almost 2,500 men, aged 40-79 years, from 1990 to 2007. 'This study has significant flaws, most notably that it is a retrospective cohort study rather than a randomised controlled trial. Furthermore, the Olmsted County population is a largely affluent Caucasian community, and therefore it is unclear as to whether these results would apply across other ethnic and socio-economic groups. However, the results are interesting at a time of ever increasing statin prescription. There is a potential for vast public health benefit if the findings of this study were reproduced across our at-risk population.'

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