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Should SSRIs be discontinued in pregnancy? Practitioner 2015;259 (1783):9

Should SSRIs be discontinued in pregnancy?

22 Jun 2015Registered users

Exposure to selective serotonin reuptake inhibitors (SSRIs) or venlafaxine in early pregnancy is associated with a small increase in the risk of birth defects but this does not appear to be due to a teratogenic effect of the drugs, a large multinational cohort study has found. The cohort consisted of 2.3 million liveborn singleton children from five Nordic countries (Denmark, Finland, Iceland, Norway and Sweden). Antidepressant exposure was defined as a redeemed prescription from 30 days before the last menstrual period until the end of the first trimester.

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