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Bland P. High prevalence of treatment resistant depression in primary carePractitioner 2014;258(1767):7-10

High prevalence of treatment resistant depression in primary care

22 Jan 2014Pais-up subscribers

Fewer than one in four depressed patients are in remission after a minimum of six weeks’ treatment with antidepressants, a UK primary care cross-sectional study has found. The data were collected during the initial stage of the CoBalT study, a randomised controlled trial of CBT augmentation for treatment-resistant depression.1 A total of 2,129 participants were recruited from 73 general practices. Eligible patients were those aged 18-75 who had been prescribed an adequate dose of antidepressant medication for at least six weeks.

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