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Bland P. Anticholinergic drugs and risk of dementia. Practitioner July/August 2018;262(1817):5

Anticholinergic drugs and risk of dementia

25 Jul 2018Pais-up subscribers

Antidepressant, urological and anti-parkinsonian drugs with definite anticholinergic effects are associated with an increased risk of incident dementia up to 20 years after exposure, a UK nested case-control study has found. The study authors conclude: 'Clinicians should continue to be vigilant with respect to the use of anticholinergic drugs, and should consider the risk of long-term cognitive effects, as well as short-term effects, associated with specific drug classes when performing their risk-benefit analysis.'

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