The Practitioner - 1868-2018: Supporting general practitioners for 150 years - How effective are antidepressants
 
 
 
 
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Bland P. How effective are antidepressants? Practitioner May 2018;262(1815):5

How effective are antidepressants?

22 May 2018Registered users

All antidepressants are more efficacious than placebo in adults with major depressive disorder, a systematic review and meta-analysis has found. Double-blind, randomised controlled trials were identified from the Cochrane Central Register of Controlled Trials and other large databases. Placebo-controlled and head-to-head trials of 21 antidepressants (a selection of first-generation and all approved second-generation antidepressants) were included.

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