The Practitioner - 1868-2018: Supporting general practitioners for 150 years - Should sertraline be used in CKD patients with depression
 
 
 
 
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Bland P. Should sertraline be used in CKD patients with depression? Practitioner Jan 2018;262(1811):5

Should sertraline be used in CKD patients with depression?

23 Jan 2018Registered users

Sertraline is ineffective in patients with chronic kidney disease (CKD) and depression, a randomised controlled trial, from the USA, has found. This study suggests that the prescription of sertraline, and indeed any SSRI, to stage 3b-5 CKD patients with depression can no longer be justified. CBT is probably the best option and there is some evidence of its efficacy in end-stage CKD patients.

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