The patient, a lady aged about 25, had suffered more or less from sick-headache or migraine from girlhood. After her marriage she had children rapidly, and being weakened in consequence, the attacks had become more frequent and violent, and had changed somewhat in character, having assumed more the character of distinct neuralgia of the first division of the fifth nerve, a common transformation. Change of air afforded relief from the attacks for a while, but as soon as she had been a short time in any place in England they began to return. She enjoyed a more complete immunity when at sea or abroad,  and during two or three journeys to the Orkneys, and on one to Malta, Egypt, and other parts of the Mediterranean, and for some time after her return she had not a single attack.