Editorial

The Practitioner 1868-2008: supporting GPs for 140 years - p5

140 years ago: Clinic of the month - p6

Rate control effective in patients with both AF and CHF - p8

Smoking during pregnancy increases risk of preterm birth - p11

Buprenorphine reduces odds of neonatal abstinence syndrome - p12

On-demand use of PDE5 inhibitors as effective as daily doses - p12-14

Effect size of antidepressants overestimated - p14

Research reviews

Amphetamine use increases risk of acute MI - p16

140 years ago: On Inhalation in Diseases of the Throat - p18

Symposium

Exercise can be effective therapy for depression - p19-24

GPs should be vigilant for eating disorders - p27-32

Updated asthma guideline will improve outcomes - p33-39

Photoguide

Vascular problems - p42-44

140 years ago: Notes and Queries - p46

Other sections

GPs are losing their core roles - p47

CPD exercise: September 2008 - p49-50

The more things change... - p51