Editorial

Consider ketamine misuse in patients with urinary symptoms - p5

QRISK2 vs Framingham - p5

Research reviews

Two-way link between diabetes and depression - p6

Ibuprofen more effective than paracetamol in childhood fever - p9

Ivabradine reduces MI in patients with LVD - p9-11

Benefits of antidepressants during pregnancy outweigh risks - p11-12

BRCA2 mutation increases mortality rate in prostate cancer - p11

Patients willing to provide vaginal swabs - p12

Symposium

GPs have central role in managing IBD - p14-21

October 2008: Tailor treatment to the patient in irritable bowel syndrome - p23-29

Guideline will aid early detection of familial hypercholesterolaemia - p30-33

CPD exercise: October 2008 - p37-38

Photoguide

Eye conditions part 1 - p40-41

Other sections

Glad to be a 21st-century GP - p42

Haslam's view: Am I having a good or bad day? - p43