Juvenile spondyloarthropathy (JSpA) is an umbrella term encompassing enthesitis-related arthritis, juvenile onset ankylosing spondylitis, juvenile psoriatic arthritis, IBD-related arthritis and reactive arthritis. Initial assessment of any childhood arthropathy should include a full blood count with differentials and inflammatory markers (CRP and ESR), which will be normal in most cases of JSpA, or may reflect a mild inflammatory response and anaemia relating to chronic disease. RF and ANA are characteristically negative. Children with JSpA should be tested for HLA-B27. Children with suspected JSpA should be referred via their GP to a tertiary paediatric rheumatology centre.