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Orrell RW. Diagnosis and management of motor neurone disease. Practitioner 2016; 260(1796):17-21

Diagnosis and management of motor neurone disease

23 Sep 2016Pais-up subscribers

Motor neurone disease is a rapidly progressive and fatal neurodegenerative condition which causes progressive weakness, with normal sensation. Key clinical presentations include bulbar (slurred or difficult speech, problems swallowing, tongue fasciculation), limb (typically in one limb with weakness and muscle wasting), respiratory (breathlessness, chest muscle fasciculation) and cognitive features (behavioural change, emotional lability, features of frontotemporal dementia).

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