Offering HIV tests to patients who present with glandular fever-like illness would improve the detection rate of HIV, a primary care study has shown. The prevalence of HIV infection in patients presenting with glandular fever-like illness in practices in Lambeth and Southwark was studied. Samples submitted to the local laboratory for a glandular fever screen between April 2009 and June 2010, with and without a concomitant HIV request, were anonymised and retrospectively tested for HIV. [With external links to current evidence]