Editorial

Is there an optimum time of day to take antihypertensive medication? - p5

Research reviews

Diabetes raises risk of cardiovascular mortality in severe aortic stenosis - p7

Bariatric surgery lowers CVD risk in severely obese patients with NAFLD - p8

Azithromycin beneficial in nonsmoking COPD patients who suffer exacerbations - p8-9

Symposium

Early diagnosis the main driver to improving outcomes in lung cancer - p11-15

Diagnosing asthma in school-age children can prove challenging - p17-20

Special Report

Optimising the management of osteoarthritis - p21-24

Prompt recognition and treatment crucial in pyelonephritis - p25-27

CPD

CPD exercise November/December 2022 - p29-30

Other sections

100 years ago: Sudden death by emotional shock - p31

150 years ago: Dr Anstie’s death and his last teaching in sanitary work - p32-33

Haslam

You don’t have to be solemn to be serious - p35