Editorial

Are antidepressants effective for back pain and osteoarthritis? - p5

Research reviews

Raised NT-proBNP predicts poor outcomes in AF without heart failure - p7

Preterm birth associated with raised risk of developmental problems at age five - p8

Pattern of heavy drinking with bingeing linked to depression - p9

Symposium

Diagnosing mild cognitive impairment can prove challenging - p11-14

Shared care central to management of substance use disorder - p15-19

Special Report

Diagnosis and management of primary hyperparathyroidism - p21-24

Other sections

150 years ago: Paralysis as a result of alcoholic excess - p29

100 years ago: Prognosis in high blood pressure - p30

Haslam

Prevention success stories often go unheralded - p31