Editorial

Physical activity significantly reduces all-cause and cause-specific mortality - p5

Research reviews

Lifestyle intervention reduces risk factors in older patients with coronary artery disease - p7

Asthma persisting from childhood to adulthood presents a distinct phenotype - p8

Evaluating therapies for depression in children and adolescents - p8-9

Patient safety incidents in opioid substitution therapy analysed - p9

Symposium

Early treatment can arrest or reverse cirrhosis - p11-14

Tailor treatment to the patient with gallstone disease - p15-19

SPECIAL REPORTS

Optimising the management of depression in children - p21-26

CPD exercise - July/August 2020 - p27-28

100 YEARS AGO

100 years ago: Where there's life there's hope - p29

150 YEARS AGO

150 years ago: Sarsaparilla therapy in syphilis - p30

Haslam

What made you choose your practice? - p31